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Experimental vascular studies using isolated rat aorta preparations reported that BPC-157 modulated vasomotor tone and increased nitric oxide generation through activation of the SrcCaveolin-1endothelial nitric oxide synthase (eNOS) signaling pathway [3]

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A randomised, double-blind, placebo-controlled research indicated that glutathione (GSH) supplementation prior to oxaliplatin therapy markedly reduced neurotoxicity while preserving therapeutic effectiveness in colorectal cancer patients [273]